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Her Energy Estrogen Balance Ultimate

  • Source of antioxidants for the maintenance of good health
  • Features I3C to promote estrogen metabolism
  • Supports a healthy estrogen balance
  • Non-GMO, gluten-free, and vegan-friendly formula

As women approach perimenopause, they often experience a shift in estrogen metabolism. (1) This shift can alter their balance in estrogen metabolite ratios, leading to an overabundance of harmful estrogens. (1) Although changes in hormone metabolism are considered part of the normal aging process, imbalanced estrogen levels can negatively impact overall health and well-being. Some estrogen metabolites, such as 16α-hydroxyestrone and 4-hydroxyestrone, can also increase a woman’s risk of chronic illnesses. (2,3)

Certain herbs, flavonoids, spices, and plant extracts are used to maintain healthy estrogen metabolite ratios and provide antioxidant protection to support women’s health and energy as they age. Cruciferous vegetables, such as broccoli, contain the anti-carcinogenic compounds I3C and sulforaphane. I3C has been shown to promote healthy estrogen metabolism by shifting the balance of estrogen metabolites in the body toward the beneficial form called 2-hydroxyestrone, while inhibiting the production of harmful forms. (2) In a clinical trial, women were supplemented with 400 mg (6–7 mg/kg) of I3C per day for two months. Urine samples confirmed that supplementation significantly increased women’s levels of the beneficial catechol estrogens and lowered their levels of endogenous estradiol and estrone. (4) A 5.5 year prospective study confirmed that a metabolic pathway leading to a higher ratio of 2-hydroxyestrone to 16α-hydroxyestrone is associated with a 40% lower risk of breast cancer in premenopausal women. (3)

Milk thistle has been used for centuries to support liver function, the liver’s ability to eliminate toxins, and antioxidant defence. (5) The seeds of the milk thistle plant contain silymarin, a mixture of active analytes that support liver function by fighting oxidative stress and stimulating the production of glutathione, a key antioxidant. The German Commission E also recommends milk thistle for liver malfunctions, such as toxin-induced liver damage, cirrhosis, and chronic inflammatory liver conditions. (6)

Small amounts of D-glucarate are made naturally by the body and are also acquired by eating oranges, apples, grapefruits, and cruciferous vegetables. (7) It plays an important role in increasing glucuronidation, the process where the liver detoxifies and eliminates chemical carcinogens, steroid hormones, and other toxins. It also helps the body excrete unhealthy estrogens and other toxins that may otherwise be reabsorbed. (7)

Ultimate Her Energy combines potent antioxidants to neutralize free radicals and protect against oxidative damage. Curcumin is the main antioxidant and anti-inflammatory compound in turmeric. A placebo-controlled study supplemented healthy middle-aged people with 80 mg of curcumin per day for four weeks. Curcumin notably increased markers of cardiovascular health and antioxidant status, while also lowering markers of stress and liver injury. (8)